Lactyl-lysine antibody
WebSep 28, 2024 · With the rapid progress of mass spectrometry-based technology and development of PLM-specific antibodies, a large number of protein substrates and sites have been identified for both well-characterized and newly discovered PLMs, in a high-throughput manner ( 22–25 ). Web0.02% Sodium azide. Stabilizer. 50% Glycerol. Storage Instruction. For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Lactyl-lysine antibody
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WebNov 19, 2024 · Histone lactylation. The production of lactate modulates angiogenesis, hypoxia and immune cell function. In Nature, Zhao and colleagues show that lactate drives the lactylation of histone lysine ... WebFeb 27, 2024 · The modulation of lactyl-CoA under several important physiological conditions, including cancer and immune cell activation, makes lactylation an exciting signaling link between metabolism and cell signaling; however, additional research into its biochemistry and physiological roles are necessary [ 30, 31 ].
WebAug 6, 2024 · The lactylated/acetylated HMGB1 is released from macrophages via exosome secretion which increases endothelium permeability. In vivo reduction of lactate … WebMA1-2024 detects human and mouse, and monkey acetylated lysine. MA1-2024 has been used successfully in Western blot, immunoprecipitation, dot blot, ChIP Assay, and immunofluorescence (cells) procedures. By Western blot, this antibody may detect a ladder of acetylated proteins in HeLa cell lysate.
WebOct 14, 2024 · Then, we explored PCSK9 regulation of the levels of protein lactylation by performed Western blot analysis using an anti-L-Lactyl lysine antibody and detected the levels of lactate in the cell supernatant of colon cancer cells by Lactate Assay Kit. WebWestern Blot: Lactyl-Lysine Antibody [NBP3-15602] - Analysis of extracts of various cell lines, using Lactyl-Lysine antibody (NBP3-15602) at 1:1000 dilution.HeLa cells,NIH/3T3 cells and C6 cells were treated by Sodium lactate(100mM) for 24h. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane.
WebHome / Products / Pan PTM Antibody / Lysine Lactylation. Sort by Default Order. Sort by Default Order; Sort by Name; Sort by Price; Sort by Date; Sort by Popularity; Sort by Rating; …
WebWestern Blot: Lactyl-Lysine Antibody [NBP3-15602] - Western blot analysis of extracts of various cell lines, using Lactyl-Lysine antibody (NBP3-15602) at 1:1000 dilution.HeLa … samsung smart tv snowy screenWebImmunocytochemistry/ Immunofluorescence - Anti-acetyl Lysine antibody [RM101] (ab190479) Immunocytochemical staining of HeLa cells labelling Acetyl Lysine with … samsung smart tv support contactWebOct 26, 2024 · Lysine lactylation (Kla) is a newly discovered histone post-translational modification (PTM), playing important roles in regulating transcription in macrophages. However, the extent of this PTM in non-histone proteins remains unknown. samsung smart tv stand screwsWebOct 26, 2024 · Histone lysine lactylation (Kla) is a newly discovered histone modification, which regulates gene expression in macrophages. In M1 macrophages, lactate is derived … samsung smart tv tem bluetoothWebAnti-acetyl Lysine antibody [RM101] (ab190479) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed specificity through extensive validation. Ethical standards compliant ... samsung smart tv thumbnail recordWebOct 23, 2024 · To confirm the modification further, we developed a pan anti-Kla antibody ... and Kla is lactyl lysine. e, f, SILAC-MS/MS quantification of histone Kla and Kac marks from MCF-7 cells, comparing ... samsung smart tv surround soundWebJan 19, 2024 · Lysine L-lactylation [K (L-la)] is a newly discovered histone mark stimulated under conditions of high glycolysis, such as the Warburg effect. K (L-la) is associated with functions that are different from the widely studied histone acetylation. samsung smart tv source button