Ctbp ogdhl
WebJan 25, 2024 · The ketoglutarate dehydrogenase complex (KGDHC) consists of three different subunits encoded by OGDH (or OGDHL), DLST, and DLD, combined in different stoichiometries. DLD subunit is shared between KGDHC and pyruvate dehydrogenase complex, branched-chain alpha-keto acid dehydrogenase complex, and the glycine … WebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. OGDHL.
Ctbp ogdhl
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WebDHS WebApr 9, 2024 · CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor; NM_001377187.1 → NP_001364116.1 C-terminal-binding protein 1 isoform 4. Status: REVIEWED. Source sequence(s) AC092535 Consensus CDS CCDS93461.1 UniProtKB/TrEMBL H0Y8U5 Conserved Domains (1) summary …
WebApr 7, 2024 · Furthermore, the higher OGDHL protein expression except the change of PLA2G2 was also found in DCM hearts, and its mRNA expression was negatively … WebAug 5, 2024 · Gene ID: 55753, updated on 5-Aug-2024 Summary The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria.
WebFeb 25, 2024 · In a 15-year-old girl (BAB4852), born of consanguineous Turkish parents, with Yoon-Bellen neurodevelopmental syndrome (YOBELN; 619701), Yoon et al. (2024) identified a homozygous c.2333C-T transition (c.2333C-T, NM_018245) in exon 18 of the OGDHL gene, resulting in a ser778-to-leu (S778L) substitution at a conserved region in … WebThe pro-metastatic role of OGDHL downregulation is most likely attributed to its upregulation of HIF-1α transactivation activity and the protein stabilization by promoting the accumulation of L-2-HG to prevent the activity of HIF-1α prolyl hydroxylases, which subsequently causes an epithelial–mesenchymal transition process in HCC cells.
The CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional corepressors. That is, regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn genes off. CtBPs do this by recruiting histone modifying enzymes that add repressive histone marks and remove activating marks. CtBP proteins can also self-as…
Webtogether, these data suggest genetic insult of DHTKD1 and OGDHL as predisposing factors in driving mito-chondrial dysfunction and molecular pathways linked to the progression of allergic inflammation. Results WES analysis of EoE. Analysis of WES data from the study cohort, including the filtering methods used to iden- ... homogeneity of variance 中文WebNov 13, 2007 · The OGDHC complex comprises multiple copies of three catalytic enzyme components, the 2-oxoglutarate dehydrogenase (OGDH/E1), the dihydrolipoamide … historical facts of chileWebThe overexpression of OGDHL also markedly suppressed the growth of HCC-LM3/OGDHL xenograft tumors in immunodeficient mice (p = 0.014; Figure 8C,D); these findings were … historical fantasy moviesWebDec 2, 2024 · We identified nine individuals from eight families carrying bi-allelic variants in the OGDHL gene through whole-exome sequencing (WES) (Figure 1 A). All groups were … homogeneity postulateWebAug 5, 2024 · OGDHL oxoglutarate dehydrogenase L Gene ID: 55753, updated on 5-Aug-2024 Gene type: protein coding Also known as: YOBELN See all available tests in GTR for this gene Go to complete Gene record for OGDHL Go to Variation Viewer for OGDHL variants Summary homogeneity politicsWebJul 31, 2024 · ogdhl沉默后，以αkg依赖性方式激活了mtorc1信号通路 ，从而诱导了在新生脂肪形成中具有关键作用的酶发生转录，进一步说明了ogdhl的功能。 前面的功能实验 … historical fancy dress childrenhttp://www.ctbtrucks.com/ historical famous people from kentucky