Cisplatin versus carboplatin

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WebAug 12, 2024 · Furthermore, although no outcome differences were observed between pediatric and adolescent patients treated with carboplatin- versus cisplatin-based regimens after controlling for other known risk factors, only 43 AYA patients (5%) treated with carboplatin-based regimens were included in this analysis. WebHotta K, Matsuo K. Long-standing debate on cisplatin- versus carboplatin-based chemotherapy in the treatment of advanced non-small cell lung cancer. J Thorac Oncol. 2007;2(1):96. 4. Hamdi T, Latta S, Jallad B, Kheir F, Alhosaini MN, Patel A. Cisplatin-induced renal salt wasting syndrome.

Cisplatin versus carboplatin: comparative review of …

WebAdvanced NSCL patients treated with carboplatin or cisplatin doublet with third-generation chemotherapy drugs showed equivalent overall survival, one-year survival, and response rate. Regarding adverse events, carboplatin caused more thrombocytopenia, and cisplatin caused more nausea/vomiting. WebMay 28, 2024 · Cisplatin is traditionally the preferred platinum agent in the curative intent setting. Data comparing the efficacy of the less toxic carboplatin to cisplatin in … can i do msc after bba

Adjuvant chemotherapy in upper tract urothelial carcinoma …

WebDec 7, 2024 · Therefore, carboplatin has been indicated as a reasonable substitute for cisplatin in ES-SCLC [ 7 ]. Recently, a meta-analysis of 663 individual patient data from … Web"Carboplatin is now being used more often than cisplatin because it can be given on an outpatient basis. It causes less kidney damage, hearing loss, nausea and vomiting and peripheral nerve damage (manifested by muscle weakness and numbness or tingling). Unfortunately, it does have more bone marrow toxicity than cisplatin." WebAdvanced NSCL patients treated with carboplatin or cisplatin doublet with third-generation chemotherapy drugs showed equivalent overall survival, one-year survival, and response … fit stitch apparel

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What is the Difference Between Carboplatin and Cisplatin

WebJun 28, 2016 · The median number of hospitalizations is 1 in the carboplatin/etoposide group versus 2 in the cisplatin/etoposide group with an odds ratio of 0.76 (95% CI, 0.65 to 0.9). For ED visits, the medians are 1 in carboplatin/etoposide and 2 is cisplatin etoposide, yielding an odds ratio of 0.82 (95% CI, 0.7 to 0.96). WebReview Efficacy and side effects of cisplatin- and carboplatin-based doublet chemotherapeutic regimens versus non-platinum-based doublet chemotherapeutic … can i do mphil after btechWebDec 7, 2024 · Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive disease with poor survival, and platinum-etoposide chemotherapy is indicated as the mainstay of treatment. In this study, we compared the efficacy and safety between the cisplatin plus etoposide (EP) and carboplatin plus etoposide (EC) regimens. A total of 1305 patients … fit stitch clothing

"WebMay 14, 2024 · Ohe Y, Ohashi Y, Kubota K, et al: Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and Vinorelbine plus Cisplatin for advanced non-small-cell lung cancer: Four-arm cooperative study in Japan. Ann Oncol 18: 317-323, 2007 Crossref, Medline, Google Scholar: 13. " - Cisplatin versus carboplatin

Cisplatin versus carboplatin

The use of cisplatin in patients after kidney... : Medicine

WebJun 1, 2016 · In comparison with carboplatin, the use of cisplatin has been more extensively evaluated in the systemic management of endometrial cancer. A recent … WebThere have been limited data comparing outcomes of carboplatin vs. cisplatin-based CRT, particularly in elderly. Material and methods: From the Surveillance, Epidemiology and End Results-Medicare registry, we identified 1878 patients >65 years of age with unresected stage III NSCLC that received concurrent CRT between 2002 and 2009.

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WebFeb 15, 2024 · Day 1 OR Day 2: Vinblastine 3mg/m 2 IV over 5-10 minutes. Day 1 OR Day 2: Doxorubicin 30mg/m 2 IV push. Day 1 OR Day 2: Cisplatin 70mg/m 2 IV over 2 hours. Repeat cycle every 2 weeks for 4-6 ... WebOct 20, 2024 · The majority of data in this space are derived from small phase 2 trials. 16,17 In this retrospective cohort study, we attempt to evaluate the efficacy of carboplatin vs cisplatin in both LS-SCLC and …

WebApr 2, 2012 · Cisplatin is associated with more GI adverse effects, neurotoxicity, and renal function impairment, and its administration requires a prolonged hydration, 5, 6 but carboplatin is associated with more myelosuppression. Although the mechanisms of action are similar, it is unclear whether carboplatin and cisplatin have the same clinical efficacy.

WebThe platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse effects/events). In total, a cancer patient can experience any combination of around 40 specific side effects. WebSep 12, 2024 · Though cisplatin and carboplatin have similar properties and structures, the body eliminates them differently. The kidneys eliminate up to 40% of cisplatin within …

WebApr 4, 2024 · Balancing factors were planned platinum agent (cisplatin vs carboplatin), preoperative radiologically or pathologically assessed nodal involvement (N0 vs N1 vs N2 vs N3), status of microscopic surgical margins (positive vs negative), and treating centre. Participants were randomly allocated (1:1) either surveillance or chemotherapy.

WebChemotherapy protocol: The TP chemotherapy regimen used was paclitaxel liposome 135 mg/m 2 d1 plus cisplatin 25 mg/m 2 d1‐3 every 3 weeks. The PF group was 5‐FU 600 mg/m 2 d1‐3 and cisplatin 25 mg/m 2 d1‐3 every 4 weeks. Chemotherapy was simultaneously supplemented with antiemetic, anti‐allergy, and other symptomatic … can i do msc after beWebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel … can i do msc physics after btech cseWebComparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis Xiao-Jun Wu, Yi Zhi, Peng He, Xiao-Zhou Zhou, Ji Zheng, Zhi-Wen Chen, Zhan-Song Zhou Institute of Urinary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of … fit stitch.comWebJun 1, 2016 · Carboplatin ( cis -diammine-cyclobutanedicarboxylato-platinum (II)) was initially believed to have “comparable” therapeutic activity with cisplatin but is associated … fit stitch clothing for womenWebJun 18, 2024 · Among chemotherapeutics with potentially lower nephrotoxicity, the inferiority of the carboplatin-Carboplatin, Etoposide, Bleomycin (CEB) versus BEP regimen has been previously demonstrated in randomized trials. [8,9] In the Horwich study, patients received either 4 series of BEP or 4 series of CEB. fitst name是什么WebCisplatin Versus Carboplatin. Carboplatin is another platinum derivate with a tenfold longer half-life than cisplatin. Due to structural differences from cisplatin, it exhibits lower reactivity and slower DNA binding kinetics in vitro. In clinical studies, the nonhematologic tolerability of carboplatin is superior to that of cisplatin, making ... fit stitchWebSep 1, 2024 · Carboplatin- and cisplatin-based chemoRT had similar incidences of death attributable to HNSCC (3-year CSM, 29% vs 26%; P=.19), which persisted in propensity score-matched analysis. In addition, no significant difference in overall survival was seen in the matched cohorts. can i do ms after mba